BENADRYL® Itch Spray

Non-stinging BENADRYL® Itch Relief Spray contains a topical antihistamine/analgesic and a skin protectant to provide fast, effective relief at the source from itchiness and pain due to allergic reactions, poison ivy, insect bites, mild sunburn or skin irritations.

Available In

  • 59 mL bottle

Symptom Relief

Provides fast, effective relief of skin itch and pain caused by:

  • Allergic reactions
  • Poison Ivy, Oak, Sumac
  • Insect bites/stings
  • Mild sunburn
  • Minor skin irritations, cuts or scrapes


Medicinal ingredients:

  • 2% w/v Diphenhydramine Hydrochloride
  • 0.1% w/v Zinc Acetate

Non-medicinal ingredients:

  • Alcohol
  • Glycerin
  • Povidone
  • Tromethamine
  • Water
  • Shake well.

Adults and children 2 years of age and older:

  • Apply to infected area not more than 3 to 4 times per day

Children under 2 years of age:

  • Consult a doctor.
  • For external use only
  • Avoid contact with eyes — If this happens, rinse thoroughly with water
  • Do not use any other drug containing diphenhydramine while using this product
  • Keep out of reach of children
  • In case of accidental ingestion, contact a doctor or a Poison Control Centre immediately
  • Store between 15°C and 30°C
  • Flammable — Keep away from fire or flame

Do not use on:

  • Broken skin
  • Raw areas of the skin
  • Chicken pox
  • Measles
  • Extensive areas of the skin

Discontinue use and consult a doctor if:

  • Condition worsens
  • Symptoms persist for more than 7 days
  • Symptoms clear up and occur again with a few days
Rated 4.1 out of 5 by 7 reviewers.
Rated 5 out of 5 by Best Product Ever For Poison Ivy This product is amazing. I suffered severe patches of poison ivy last year and tried almost every product with very little relief. First bout of poison ivy this year and I gave this product a try with instant relief! June 14, 2016
Rated 5 out of 5 by great product itch relief spray due to insect bites reliefs pain and itch September 2, 2015
Rated 5 out of 5 by Life Saver! Anyone who suffers from allergic reactions due to mosquitoes, please look for this! It has literally dissipated my fear, and given me courage to brave the outdoors (bites usually = welts and rashes as big as loonies, that stay with me for months). This is a topical Benedryl spray, that makes brilliant sense (to me)! It actually relieved the initial pain and itch, as well seems to have reduced the swelling permanently. LIFE SAVER! June 16, 2015
Rated 5 out of 5 by Relieves itching and swelling from mosquito and black fly bites! Great product! I react strongly with redness, swelling and intense itching when bitten by black flies and mosquitoes. This weekend I got bitten many times on my feet, ankles, lower legs, and toes. I was really was miserable and consumed with scratching the bites, which in turn caused more swelling and itchiness, especially while trying to sleep at night. The next day, I remembered the Benadryl extra strength cooling spray that my daughter bought last summer. I sprayed it on liberally and it really helped stop the itching and swelling. June 2, 2015
Rated 4 out of 5 by Spray was more effective than the stick I carry either the spray or the stick in my bag wherever I go in the summer. Generally, I've found that the spray prevents swelling and itching of mosquito bites more effectively if applied right after getting bitten (I react very severely so any relief of symptoms is welcome). The stick is more convenient for a purse and not as messy. May 16, 2014
Rated 4 out of 5 by This worked great!! Had major itching from rash and irritation, sprayed benadryl and withing minutes the itching was gone, great product March 24, 2014
Rated 1 out of 5 by Intensified the condition! It increased the itching, heat and pain! I do not recommend this product at all! February 8, 2014
  • 2016-06-28 T12:00:28.825-05:00
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